Sequential disruption of SPLASH-identified vRNA–vRNA interactions challenges their role in influenza A virus genome packaging

A fundamental step in the influenza A virus (IAV) replication cycle is the coordinated packaging of eight distinct genomic RNA segments (i.e. vRNAs) into a viral particle. Although this process is thought to be controlled by specific vRNA–vRNA interactions between the genome segments, few functional...

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Detalles Bibliográficos
Autores principales: Jakob, Celia, Lovate, Gabriel L, Desirò, Daniel, Gießler, Lara, Smyth, Redmond P, Marquet, Roland, Lamkiewicz, Kevin, Marz, Manja, Schwemmle, Martin, Bolte, Hardin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325904/
https://www.ncbi.nlm.nih.gov/pubmed/37224537
http://dx.doi.org/10.1093/nar/gkad442

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