Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity

Iron metabolism is closely associated with the pathogenesis of obesity. However, the mechanism of the iron-dependent regulation of adipocyte differentiation remains unclear. Here, we show that iron is essential for rewriting of epigenetic marks during adipocyte differentiation. Iron supply through l...

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Detalles Bibliográficos
Autores principales: Suzuki, Tomohiro, Komatsu, Tetsuro, Shibata, Hiroshi, Tanioka, Akiko, Vargas, Diana, Kawabata-Iwakawa, Reika, Miura, Fumihito, Masuda, Shinnosuke, Hayashi, Mayuko, Tanimura-Inagaki, Kyoko, Morita, Sumiyo, Kohmaru, Junki, Adachi, Koji, Tobo, Masayuki, Obinata, Hideru, Hirayama, Tasuku, Kimura, Hiroshi, Sakai, Juro, Nagasawa, Hideko, Itabashi, Hideyuki, Hatada, Izuho, Ito, Takashi, Inagaki, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325906/
https://www.ncbi.nlm.nih.gov/pubmed/37158274
http://dx.doi.org/10.1093/nar/gkad342

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