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Knockout of protein phosphatase 1 in Leishmania major reveals its role during RNA polymerase II transcription termination

The genomes of kinetoplastids are organized into polycistronic transcription units that are flanked by a modified DNA base (base J, beta-D-glucosyl-hydroxymethyluracil). Previous work established a role of base J in promoting RNA polymerase II (Pol II) termination in Leishmania major and Trypanosoma...

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Detalles Bibliográficos
Autores principales: Kieft, Rudo, Zhang, Yang, Yan, Haidong, Schmitz, Robert J, Sabatini, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325913/
https://www.ncbi.nlm.nih.gov/pubmed/37194692
http://dx.doi.org/10.1093/nar/gkad394