DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding

CpG methylation generally occurs on both DNA strands and is essential for mammalian development and differentiation. Until recently, hemimethylation, in which only one strand is methylated, was considered to be simply a transitory state generated during DNA synthesis. The discovery that a subset of...

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Detalles Bibliográficos
Autores principales: Thomas, Stacey L, Xu, Ting-Hai, Carpenter, Brittany L, Pierce, Steven E, Dickson, Bradley M, Liu, Minmin, Liang, Gangning, Jones, Peter A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325916/
https://www.ncbi.nlm.nih.gov/pubmed/37094063
http://dx.doi.org/10.1093/nar/gkad293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325916/
https://www.ncbi.nlm.nih.gov/pubmed/37094063
http://dx.doi.org/10.1093/nar/gkad293

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