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DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding
CpG methylation generally occurs on both DNA strands and is essential for mammalian development and differentiation. Until recently, hemimethylation, in which only one strand is methylated, was considered to be simply a transitory state generated during DNA synthesis. The discovery that a subset of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325916/ https://www.ncbi.nlm.nih.gov/pubmed/37094063 http://dx.doi.org/10.1093/nar/gkad293 |