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Effect of pharmacokinetics and pharmacogenomics in adults with allogeneic hematopoietic cell transplantation conditioned with Busulfan

Busulfan (Bu) combined with cyclophosphamide (Cy) is commonly used as a myeloablative conditioning regimen for allogeneic hematopoietic cell transplantation (allo-HCT). There is inter-individual variability of Bu pharmacokinetics (PK) and hence in toxicity and efficacy. The introduction of therapeut...

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Detalles Bibliográficos
Autores principales:	Seydoux, Claire, Uppugunduri, Chakradhara Rao Satyanarayana, Medinger, Michael, Nava, Tiago, Halter, Joerg, Heim, Dominik, Chalandon, Yves, Schanz, Urs, Nair, Gayathri, Cantoni, Nathan, Passweg, Jakob R., Ansari, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325946/ https://www.ncbi.nlm.nih.gov/pubmed/37085674 http://dx.doi.org/10.1038/s41409-023-01963-z

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