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E3 ligase MG53 suppresses tumor growth by degrading cyclin D1

Due to the essential role of cyclin D1 in regulating transition from G1 to S phase in cell cycle, aberrant cyclin D1 expression is a major oncogenic event in many types of cancers. In particular, the dysregulation of ubiquitination-dependent degradation of cyclin D1 contributes to not only the patho...

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Detalles Bibliográficos
Autores principales:	Fang, Meng, Wu, Hong-Kun, Pei, Yumeng, Zhang, Yan, Gao, Xiangyu, He, Yanyun, Chen, Gengjia, Lv, Fengxiang, Jiang, Peng, Li, Yumei, Li, Wenwen, Wang, Lin, Ji, Jiafu, Hu, Xinli, Xiao, Rui-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326024/ https://www.ncbi.nlm.nih.gov/pubmed/37414783 http://dx.doi.org/10.1038/s41392-023-01458-9

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