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Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability

Variability in disease severity caused by a microbial pathogen is impacted by each infection representing a unique combination of host and pathogen genomes. Here, we show that the outcome of invasive Streptococcus pyogenes infection is regulated by an interplay between human STING genotype and bacte...

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Detalles Bibliográficos
Autores principales:	Movert, Elin, Bolarin, Jaume Salgado, Valfridsson, Christine, Velarde, Jorge, Skrede, Steinar, Nekludov, Michael, Hyldegaard, Ole, Arnell, Per, Svensson, Mattias, Norrby-Teglund, Anna, Cho, Kyu Hong, Elhaik, Eran, Wessels, Michael R., Råberg, Lars, Carlsson, Fredric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326033/ https://www.ncbi.nlm.nih.gov/pubmed/37414832 http://dx.doi.org/10.1038/s41467-023-39771-0

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