Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays

The advent of combined antiretroviral therapy (cART) has been instrumental in controlling HIV-1 replication and transmission and decreasing associated morbidity and mortality. However, cART alone is not able to cure HIV-1 due to the presence of long-lived, latently infected immune cells, which re-se...

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Detalles Bibliográficos
Autores principales: Kuzmichev, Yury V., Lackman-Smith, Carol, Bakkour, Sonia, Wiegand, Ann, Bale, Michael J., Musick, Andrew, Bernstein, Wendy, Aronson, Naomi, Ake, Julie, Tovanabutra, Sodsai, Stone, Mars, Ptak, Roger G., Kearney, Mary F., Busch, Michael P., Wonderlich, Elizabeth R., Kulpa, Deanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326067/
https://www.ncbi.nlm.nih.gov/pubmed/37414788
http://dx.doi.org/10.1038/s41598-023-37223-9

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