PAX5 P80R-mutated B-cell acute lymphoblastic leukemia with transformation to histiocytic sarcoma: clonal evolution assessment using NGS-based immunoglobulin clonality and mutation analysis

Clonality assessment by the detection of immunoglobulin (IG) gene rearrangements is an important method to determine whether two concurrent or subsequent lymphoid malignancies in one patient are clonally related. Here, we report the detailed clonality analysis in a patient with a diagnosis of B-cell...

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Detalles Bibliográficos
Autores principales: Kroeze, Leonie I., Scheijen, B., Hebeda, K. M., Rijntjes, J., Luijks, J. A. C. W., Evers, D., Hobo, W., Groenen, P. J. T. A., van den Brand, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326092/
https://www.ncbi.nlm.nih.gov/pubmed/36241730
http://dx.doi.org/10.1007/s00428-022-03428-y

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