Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci

We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci, a rare entity recently described by Jennifer N. Stall and Robert H. Young in a series of sixteen cases in 2019, displaying features differing from conventional adult granulosa cell...

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Autores principales: Fischer, Anne Kristin, Schömig-Markiefka, Birgid, Heydt, Carina, Ratiu, Dominik, Mallmann, Peter, Meinel, Jörn, Büttner, Reinhard, Schmidt, Dietmar, Quaas, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326121/
https://www.ncbi.nlm.nih.gov/pubmed/36399188
http://dx.doi.org/10.1007/s00428-022-03452-y
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author Fischer, Anne Kristin
Schömig-Markiefka, Birgid
Heydt, Carina
Ratiu, Dominik
Mallmann, Peter
Meinel, Jörn
Büttner, Reinhard
Schmidt, Dietmar
Quaas, Alexander
author_facet Fischer, Anne Kristin
Schömig-Markiefka, Birgid
Heydt, Carina
Ratiu, Dominik
Mallmann, Peter
Meinel, Jörn
Büttner, Reinhard
Schmidt, Dietmar
Quaas, Alexander
author_sort Fischer, Anne Kristin
collection PubMed
description We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci, a rare entity recently described by Jennifer N. Stall and Robert H. Young in a series of sixteen cases in 2019, displaying features differing from conventional adult granulosa cell tumour. Our aim is to specify the morphologic and molecular particularities of this presumably underrecognized finding, with a short presentation of the typical clinical context. Awareness of this rare and challenging neoplasm with indeterminate clinical course is crucial in routine diagnostics.
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spelling pubmed-103261212023-07-08 Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci Fischer, Anne Kristin Schömig-Markiefka, Birgid Heydt, Carina Ratiu, Dominik Mallmann, Peter Meinel, Jörn Büttner, Reinhard Schmidt, Dietmar Quaas, Alexander Virchows Arch Brief Report We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci, a rare entity recently described by Jennifer N. Stall and Robert H. Young in a series of sixteen cases in 2019, displaying features differing from conventional adult granulosa cell tumour. Our aim is to specify the morphologic and molecular particularities of this presumably underrecognized finding, with a short presentation of the typical clinical context. Awareness of this rare and challenging neoplasm with indeterminate clinical course is crucial in routine diagnostics. Springer Berlin Heidelberg 2022-11-18 2023 /pmc/articles/PMC10326121/ /pubmed/36399188 http://dx.doi.org/10.1007/s00428-022-03452-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Report
Fischer, Anne Kristin
Schömig-Markiefka, Birgid
Heydt, Carina
Ratiu, Dominik
Mallmann, Peter
Meinel, Jörn
Büttner, Reinhard
Schmidt, Dietmar
Quaas, Alexander
Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
title Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
title_full Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
title_fullStr Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
title_full_unstemmed Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
title_short Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
title_sort incidental foxl2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326121/
https://www.ncbi.nlm.nih.gov/pubmed/36399188
http://dx.doi.org/10.1007/s00428-022-03452-y
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