Case Report: Two clinical cases of Wilms tumor comorbid to gingival fibromatosis in young children with constitutionally mutated REST

INTRODUCTION: Nephroblastoma (Wilms tumor (WT)) is an embryonal tumor accounting for >90% of pediatric renal cancers. About 10% of WTs harbor pathogenic germline mutations. The REST gene, classified as a putative tumor suppressor, is affected in 2% of WTs. High-throughput molecular methods facili...

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Detalles Bibliográficos
Autores principales: Salomatina, Anastasiya S., Yasko, Liudmila A., Kurnikova, Maria A., Mareeva, Yulia M., Abasov, Ruslan K., Gegeliya, Nina V., Mitrofanova, Anna M., Usman, Natalia Y., Novichkova, Galina A., Druy, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326162/
https://www.ncbi.nlm.nih.gov/pubmed/37427114
http://dx.doi.org/10.3389/fonc.2023.1192489

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