Varicella zoster virus-associated non-necrotizing retinitis: case report

PURPOSE: To describe clinical features and the course of a case of non-necrotizing herpetic retinitis secondary to Varicella zoster virus (VZV). MATERIEL AND METHODS: A single case report documented with multimodal imaging. RESULTS: A 52-year-old female patient with a past medical history of diabete...

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Autores principales: Rym, Maamouri, Yasmine, Houman, Marwa, Abdelaziz, Imen, Helal, Monia, Cheour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326174/
https://www.ncbi.nlm.nih.gov/pubmed/37410194
http://dx.doi.org/10.1186/s12348-023-00353-2
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author Rym, Maamouri
Yasmine, Houman
Marwa, Abdelaziz
Imen, Helal
Monia, Cheour
author_facet Rym, Maamouri
Yasmine, Houman
Marwa, Abdelaziz
Imen, Helal
Monia, Cheour
author_sort Rym, Maamouri
collection PubMed
description PURPOSE: To describe clinical features and the course of a case of non-necrotizing herpetic retinitis secondary to Varicella zoster virus (VZV). MATERIEL AND METHODS: A single case report documented with multimodal imaging. RESULTS: A 52-year-old female patient with a past medical history of diabetes mellitus who presented with painful red right eye (OD). Ophthalmic examination showed perilimbal conjunctival nodule, granulomatous anterior uveitis, sectoral iris atrophy and increased intraocular pressure. Fundus examination in OD revealed posterior multifocal retinitis. Left eye examination was unremarkable. Polymerase chain reaction (PCR) of aqueous humor sample confirmed the presence of VZV DNA. Systemic antiviral therapy allowed the improvement of intraocular inflammation and disappearance of the retinal non necrotizing retinitis after one year of regular follow-up. CONCLUSION: Non-necrotizing retinitis is an underdiagnosed form of VZV ocular infection.
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spelling pubmed-103261742023-07-08 Varicella zoster virus-associated non-necrotizing retinitis: case report Rym, Maamouri Yasmine, Houman Marwa, Abdelaziz Imen, Helal Monia, Cheour J Ophthalmic Inflamm Infect Correspondence PURPOSE: To describe clinical features and the course of a case of non-necrotizing herpetic retinitis secondary to Varicella zoster virus (VZV). MATERIEL AND METHODS: A single case report documented with multimodal imaging. RESULTS: A 52-year-old female patient with a past medical history of diabetes mellitus who presented with painful red right eye (OD). Ophthalmic examination showed perilimbal conjunctival nodule, granulomatous anterior uveitis, sectoral iris atrophy and increased intraocular pressure. Fundus examination in OD revealed posterior multifocal retinitis. Left eye examination was unremarkable. Polymerase chain reaction (PCR) of aqueous humor sample confirmed the presence of VZV DNA. Systemic antiviral therapy allowed the improvement of intraocular inflammation and disappearance of the retinal non necrotizing retinitis after one year of regular follow-up. CONCLUSION: Non-necrotizing retinitis is an underdiagnosed form of VZV ocular infection. Springer Berlin Heidelberg 2023-07-06 /pmc/articles/PMC10326174/ /pubmed/37410194 http://dx.doi.org/10.1186/s12348-023-00353-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Correspondence
Rym, Maamouri
Yasmine, Houman
Marwa, Abdelaziz
Imen, Helal
Monia, Cheour
Varicella zoster virus-associated non-necrotizing retinitis: case report
title Varicella zoster virus-associated non-necrotizing retinitis: case report
title_full Varicella zoster virus-associated non-necrotizing retinitis: case report
title_fullStr Varicella zoster virus-associated non-necrotizing retinitis: case report
title_full_unstemmed Varicella zoster virus-associated non-necrotizing retinitis: case report
title_short Varicella zoster virus-associated non-necrotizing retinitis: case report
title_sort varicella zoster virus-associated non-necrotizing retinitis: case report
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326174/
https://www.ncbi.nlm.nih.gov/pubmed/37410194
http://dx.doi.org/10.1186/s12348-023-00353-2
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