Pain and Inflammation as Mediators of Tofacitinib Treatment Effect on Fatigue in Patients with Ankylosing Spondylitis: A Mediation Analysis

INTRODUCTION: Tofacitinib is an oral Janus kinase inhibitor for treatment of ankylosing spondylitis (AS). Using mediation modelling, we describe interrelationships between fatigue, pain, morning stiffness, C-reactive protein (CRP) and tofacitinib treatment in patients with AS. METHODS: Data from pha...

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Detalles Bibliográficos
Autores principales: Kristensen, Lars Erik, Navarro-Compán, Victoria, Magrey, Marina, Bushmakin, Andrew G., Cappelleri, Joseph C., Yndestad, Arne, Dina, Oluwaseyi, Taylor, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326212/
https://www.ncbi.nlm.nih.gov/pubmed/37351781
http://dx.doi.org/10.1007/s40744-023-00570-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326212/
https://www.ncbi.nlm.nih.gov/pubmed/37351781
http://dx.doi.org/10.1007/s40744-023-00570-0

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