Surgical management of deep dermatophytosis in a patient with CARD9 deficiency

Deep dermatophytosis is a dermal infection caused by Dermatophytes. It can cause deeper dermal dermatophytosis, Majocchi’s granuloma, dermatophytic pseudomycetoma or a widespread infection. CARD9 deficiency is a known risk factor in the Mediterranean region, first reported in 1964 in Morocco. We rep...

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Detalles Bibliográficos
Autores principales: El Maati, Maha, Berjaou, Zakia, Hammouch, Zaineb, Khachani, Kenza, Moustakbal, Iliass, Meziane, Meryem, Ismaili, Nadia, Benzekri, Laila, Aoufi, Sara, Mazouz, Samir, Senouci, Karima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326240/
https://www.ncbi.nlm.nih.gov/pubmed/37426045
http://dx.doi.org/10.1093/jscr/rjad388
Descripción
Sumario:Deep dermatophytosis is a dermal infection caused by Dermatophytes. It can cause deeper dermal dermatophytosis, Majocchi’s granuloma, dermatophytic pseudomycetoma or a widespread infection. CARD9 deficiency is a known risk factor in the Mediterranean region, first reported in 1964 in Morocco. We report a case of 23-year-old man with a scarring alopecia who presented with subcutaneous abscesses topped off with a large ringworm infection. Mycotic analysis revealed a Trichophyton Rubrum deep dermatophytosis. The molecular study revealed a CARD9 mutation confirming dermatophytosis with parotid and lymph nodes involvement. The patient underwent successful drainage surgery of the abscesses alongside medical treatment including antifungal agents and he was discharged after an uneventful postoperative course.

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