Surgical management of deep dermatophytosis in a patient with CARD9 deficiency

Deep dermatophytosis is a dermal infection caused by Dermatophytes. It can cause deeper dermal dermatophytosis, Majocchi’s granuloma, dermatophytic pseudomycetoma or a widespread infection. CARD9 deficiency is a known risk factor in the Mediterranean region, first reported in 1964 in Morocco. We rep...

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Autores principales: El Maati, Maha, Berjaou, Zakia, Hammouch, Zaineb, Khachani, Kenza, Moustakbal, Iliass, Meziane, Meryem, Ismaili, Nadia, Benzekri, Laila, Aoufi, Sara, Mazouz, Samir, Senouci, Karima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326240/
https://www.ncbi.nlm.nih.gov/pubmed/37426045
http://dx.doi.org/10.1093/jscr/rjad388
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author El Maati, Maha
Berjaou, Zakia
Hammouch, Zaineb
Khachani, Kenza
Moustakbal, Iliass
Meziane, Meryem
Ismaili, Nadia
Benzekri, Laila
Aoufi, Sara
Mazouz, Samir
Senouci, Karima
author_facet El Maati, Maha
Berjaou, Zakia
Hammouch, Zaineb
Khachani, Kenza
Moustakbal, Iliass
Meziane, Meryem
Ismaili, Nadia
Benzekri, Laila
Aoufi, Sara
Mazouz, Samir
Senouci, Karima
author_sort El Maati, Maha
collection PubMed
description Deep dermatophytosis is a dermal infection caused by Dermatophytes. It can cause deeper dermal dermatophytosis, Majocchi’s granuloma, dermatophytic pseudomycetoma or a widespread infection. CARD9 deficiency is a known risk factor in the Mediterranean region, first reported in 1964 in Morocco. We report a case of 23-year-old man with a scarring alopecia who presented with subcutaneous abscesses topped off with a large ringworm infection. Mycotic analysis revealed a Trichophyton Rubrum deep dermatophytosis. The molecular study revealed a CARD9 mutation confirming dermatophytosis with parotid and lymph nodes involvement. The patient underwent successful drainage surgery of the abscesses alongside medical treatment including antifungal agents and he was discharged after an uneventful postoperative course.
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spelling pubmed-103262402023-07-08 Surgical management of deep dermatophytosis in a patient with CARD9 deficiency El Maati, Maha Berjaou, Zakia Hammouch, Zaineb Khachani, Kenza Moustakbal, Iliass Meziane, Meryem Ismaili, Nadia Benzekri, Laila Aoufi, Sara Mazouz, Samir Senouci, Karima J Surg Case Rep Case Report Deep dermatophytosis is a dermal infection caused by Dermatophytes. It can cause deeper dermal dermatophytosis, Majocchi’s granuloma, dermatophytic pseudomycetoma or a widespread infection. CARD9 deficiency is a known risk factor in the Mediterranean region, first reported in 1964 in Morocco. We report a case of 23-year-old man with a scarring alopecia who presented with subcutaneous abscesses topped off with a large ringworm infection. Mycotic analysis revealed a Trichophyton Rubrum deep dermatophytosis. The molecular study revealed a CARD9 mutation confirming dermatophytosis with parotid and lymph nodes involvement. The patient underwent successful drainage surgery of the abscesses alongside medical treatment including antifungal agents and he was discharged after an uneventful postoperative course. Oxford University Press 2023-07-05 /pmc/articles/PMC10326240/ /pubmed/37426045 http://dx.doi.org/10.1093/jscr/rjad388 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
El Maati, Maha
Berjaou, Zakia
Hammouch, Zaineb
Khachani, Kenza
Moustakbal, Iliass
Meziane, Meryem
Ismaili, Nadia
Benzekri, Laila
Aoufi, Sara
Mazouz, Samir
Senouci, Karima
Surgical management of deep dermatophytosis in a patient with CARD9 deficiency
title Surgical management of deep dermatophytosis in a patient with CARD9 deficiency
title_full Surgical management of deep dermatophytosis in a patient with CARD9 deficiency
title_fullStr Surgical management of deep dermatophytosis in a patient with CARD9 deficiency
title_full_unstemmed Surgical management of deep dermatophytosis in a patient with CARD9 deficiency
title_short Surgical management of deep dermatophytosis in a patient with CARD9 deficiency
title_sort surgical management of deep dermatophytosis in a patient with card9 deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326240/
https://www.ncbi.nlm.nih.gov/pubmed/37426045
http://dx.doi.org/10.1093/jscr/rjad388
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