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Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries

Pulmonary hypertension (PH) is an insidious pulmonary vasculopathy with high mortality and morbidity and its underlying pathogenesis is still poorly delineated. The hyperproliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs) contributes to pulmonary vascular remodeli...

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Detalles Bibliográficos
Autores principales: Li, Bingbing, Teng, Chao, Yu, Huiling, Jiang, Xiaohong, Xing, Xuyang, Jiang, Qi, Lin, Chenshi, Zhao, Zongmin, Zhang, Ruifeng, He, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326245/
https://www.ncbi.nlm.nih.gov/pubmed/37425053
http://dx.doi.org/10.1016/j.apsb.2022.12.002