Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations

Autism Spectrum Disorder (ASD) is characterized mainly by social and sensory-motor abnormal and repetitive behavior patterns. Over hundreds of genes and thousands of genetic variants were reported to be highly penetrant and causative of ASD. Many of these mutations cause comorbidities such as epilep...

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Detalles Bibliográficos
Autores principales: Hussein, Yara, Tripathi, Utkarsh, Choudhary, Ashwani, Nayak, Ritu, Peles, David, Rosh, Idan, Rabinski, Tatiana, Djamus, Jose, Vatine, Gad David, Spiegel, Ronen, Garin-Shkolnik, Tali, Stern, Shani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326262/
https://www.ncbi.nlm.nih.gov/pubmed/37414777
http://dx.doi.org/10.1038/s41398-023-02535-x

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