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Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA

Mevalonate metabolism plays an important role in regulating tumor growth and progression; however, its role in immune evasion and immune checkpoint modulation remains unclear. Here, we found that non-small cell lung cancer (NSCLC) patients with higher plasma mevalonate response better to anti-PD-(L)...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenxin, Pan, Xiaohui, Xu, Yanjun, Guo, Hongjie, Zheng, Mingming, Chen, Xi, Wu, Honghai, Luan, Fengming, He, Qiaojun, Ding, Ling, Yang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326297/ https://www.ncbi.nlm.nih.gov/pubmed/37425040 http://dx.doi.org/10.1016/j.apsb.2023.04.002

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