Overexpressed SIRT6 ameliorates doxorubicin-induced cardiotoxicity and potentiates the therapeutic efficacy through metabolic remodeling

Since the utilization of anthracyclines in cancer therapy, severe cardiotoxicity has become a major obstacle. The major challenge in treating cancer patients with anthracyclines is minimizing cardiotoxicity without compromising antitumor efficacy. Herein, histone deacetylase SIRT6 expression was red...

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Detalles Bibliográficos
Autores principales: Peng, Kezheng, Zeng, Chenye, Gao, Yuqi, Liu, Binliang, Li, Liyuan, Xu, Kang, Yin, Yuemiao, Qiu, Ying, Zhang, Mingkui, Ma, Fei, Wang, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326298/
https://www.ncbi.nlm.nih.gov/pubmed/37425037
http://dx.doi.org/10.1016/j.apsb.2023.03.019

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