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Detection of endogenous translesion DNA synthesis in single mammalian cells

Translesion DNA synthesis (TLS) is an evolutionarily conserved process that cells activate to tolerate DNA damage. TLS facilitates proliferation under DNA damage conditions and is exploited by cancer cells to gain therapy resistance. It has been so far challenging to analyze endogenous TLS factors s...

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Detalles Bibliográficos
Autores principales:	Egger, Tom, Aze, Antoine, Maiorano, Domenico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326377/ https://www.ncbi.nlm.nih.gov/pubmed/37426760 http://dx.doi.org/10.1016/j.crmeth.2023.100501

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