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Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage

INTRODUCTION: We report a very unique clinical presentation of a patient who complained, after a left parietal brain damage, about feeling tactile stimulations on his right upper limb without being able to localize them. METHODS: Using a single case study approach, we report three experiments relyin...

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Autores principales: Have, Laurence, Quesque, François, Priot, Anne-Emmanuelle, Chastres, Véronique, Revol, Patrice, Delporte, Ludovic, Chabanat, Eric, Obadia, Nathalie, Cotton, François, Reilly, Karen T., Rossetti, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326386/
https://www.ncbi.nlm.nih.gov/pubmed/37425290
http://dx.doi.org/10.3389/fnhum.2023.1167489
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author Have, Laurence
Quesque, François
Priot, Anne-Emmanuelle
Chastres, Véronique
Revol, Patrice
Delporte, Ludovic
Chabanat, Eric
Obadia, Nathalie
Cotton, François
Reilly, Karen T.
Rossetti, Yves
author_facet Have, Laurence
Quesque, François
Priot, Anne-Emmanuelle
Chastres, Véronique
Revol, Patrice
Delporte, Ludovic
Chabanat, Eric
Obadia, Nathalie
Cotton, François
Reilly, Karen T.
Rossetti, Yves
author_sort Have, Laurence
collection PubMed
description INTRODUCTION: We report a very unique clinical presentation of a patient who complained, after a left parietal brain damage, about feeling tactile stimulations on his right upper limb without being able to localize them. METHODS: Using a single case study approach, we report three experiments relying on several custom-made tasks to explore the different levels of somatosensory information processing, ranging from somato-sensation to somato-representation. RESULTS: Our results showed a preserved ability to localize tactile stimuli applied on the right upper limb when using pointing responses while the ability to localize was less efficient when having to name the stimulated part (akin Numbsense). When the stimuli were applied on more distal locations (i.e., on the hand and on fingers), the number of correct responses decreased significantly independently of the modality of response. Finally, when visually presented with a stimulus delivered on the hand of an examiner in synchrony with the stimulation on the hidden hand of the patient, responses were largely influenced by the visual information available. Altogether, the convergence of these different customized tasks revealed an absence of autotopagnosia for motor responses for the right upper limb, associated with altered abilities to discriminate stimulus applied on distal and restricted/closer zones in the hand. DISCUSSION: The somato-representation of our patient seemed to significantly rely on visual information, leading to striking deficits to localize tactile stimuli when vision and somesthesic afferences are discordant. This case report offers a clinical illustration of pathological imbalance between vision and somesthesia. Implications of these troubles in somato-representation on higher cognitive level processes are discussed.
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spelling pubmed-103263862023-07-08 Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage Have, Laurence Quesque, François Priot, Anne-Emmanuelle Chastres, Véronique Revol, Patrice Delporte, Ludovic Chabanat, Eric Obadia, Nathalie Cotton, François Reilly, Karen T. Rossetti, Yves Front Hum Neurosci Neuroscience INTRODUCTION: We report a very unique clinical presentation of a patient who complained, after a left parietal brain damage, about feeling tactile stimulations on his right upper limb without being able to localize them. METHODS: Using a single case study approach, we report three experiments relying on several custom-made tasks to explore the different levels of somatosensory information processing, ranging from somato-sensation to somato-representation. RESULTS: Our results showed a preserved ability to localize tactile stimuli applied on the right upper limb when using pointing responses while the ability to localize was less efficient when having to name the stimulated part (akin Numbsense). When the stimuli were applied on more distal locations (i.e., on the hand and on fingers), the number of correct responses decreased significantly independently of the modality of response. Finally, when visually presented with a stimulus delivered on the hand of an examiner in synchrony with the stimulation on the hidden hand of the patient, responses were largely influenced by the visual information available. Altogether, the convergence of these different customized tasks revealed an absence of autotopagnosia for motor responses for the right upper limb, associated with altered abilities to discriminate stimulus applied on distal and restricted/closer zones in the hand. DISCUSSION: The somato-representation of our patient seemed to significantly rely on visual information, leading to striking deficits to localize tactile stimuli when vision and somesthesic afferences are discordant. This case report offers a clinical illustration of pathological imbalance between vision and somesthesia. Implications of these troubles in somato-representation on higher cognitive level processes are discussed. Frontiers Media S.A. 2023-06-23 /pmc/articles/PMC10326386/ /pubmed/37425290 http://dx.doi.org/10.3389/fnhum.2023.1167489 Text en Copyright © 2023 Have, Quesque, Priot, Chastres, Revol, Delporte, Chabanat, Obadia, Cotton, Reilly and Rossetti. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Have, Laurence
Quesque, François
Priot, Anne-Emmanuelle
Chastres, Véronique
Revol, Patrice
Delporte, Ludovic
Chabanat, Eric
Obadia, Nathalie
Cotton, François
Reilly, Karen T.
Rossetti, Yves
Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
title Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
title_full Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
title_fullStr Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
title_full_unstemmed Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
title_short Feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
title_sort feeling without localizing: exploring tactile misperception in a patient with uncommon parietal left brain damage
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326386/
https://www.ncbi.nlm.nih.gov/pubmed/37425290
http://dx.doi.org/10.3389/fnhum.2023.1167489
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