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The KaryoCreate technology generates specific aneuploid karyotypes on demand

In a recent issue of Cell, Bosco et al. present an innovative methodology named KaryoCreate that allows the generation of chromosome-specific aneuploidy in human cells in order to investigate the ontogenesis and the multifaceted aspects of aneuploidy in physio-pathological contexts.

Detalles Bibliográficos
Autores principales: Angrisani, Annapaola, Fachinetti, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326432/
https://www.ncbi.nlm.nih.gov/pubmed/37426746
http://dx.doi.org/10.1016/j.crmeth.2023.100514
Descripción
Sumario:In a recent issue of Cell, Bosco et al. present an innovative methodology named KaryoCreate that allows the generation of chromosome-specific aneuploidy in human cells in order to investigate the ontogenesis and the multifaceted aspects of aneuploidy in physio-pathological contexts.