Affinity-enhanced RNA-binding domains as tools to understand RNA recognition

Understanding how the RNA-binding domains of a protein regulator are used to recognize its RNA targets is a key problem in RNA biology, but RNA-binding domains with very low affinity do not perform well in the methods currently available to characterize protein-RNA interactions. Here, we propose to...

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Detalles Bibliográficos
Autores principales: Chaves-Arquero, Belén, Collins, Katherine M., Abis, Giancarlo, Kelly, Geoff, Christodoulou, Evangelos, Taylor, Ian A., Ramos, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326445/
https://www.ncbi.nlm.nih.gov/pubmed/37426752
http://dx.doi.org/10.1016/j.crmeth.2023.100508

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