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An information theoretic approach to detecting spatially varying genes

A key step in spatial transcriptomics is identifying genes with spatially varying expression patterns. We adopt an information theoretic perspective to this problem by equating the degree of spatial coherence with the Jensen-Shannon divergence between pairs of nearby cells and pairs of distant cells...

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Detalles Bibliográficos
Autores principales: Jones, Daniel C., Danaher, Patrick, Kim, Youngmi, Beechem, Joseph M., Gottardo, Raphael, Newell, Evan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326450/
https://www.ncbi.nlm.nih.gov/pubmed/37426750
http://dx.doi.org/10.1016/j.crmeth.2023.100507

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