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Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter

BACKGROUND: To observe the postoperative recovery following ureteral dilation in primary obstructive megaureter (POM) after ureteral implantation, and evaluate the risk factors affecting ureter diameter resolution. MATERIALS AND METHODS: A retrospective study was performed in patients with POM who u...

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Autores principales: He, Yan, Wu, Xuemin, Xu, Yingrui, Liu, Zhaoquan, Du, Guoqiang, Wu, Xiangyu, Liu, Wei, Wu, Rongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326513/
https://www.ncbi.nlm.nih.gov/pubmed/37425259
http://dx.doi.org/10.3389/fped.2023.1164474
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author He, Yan
Wu, Xuemin
Xu, Yingrui
Liu, Zhaoquan
Du, Guoqiang
Wu, Xiangyu
Liu, Wei
Wu, Rongde
author_facet He, Yan
Wu, Xuemin
Xu, Yingrui
Liu, Zhaoquan
Du, Guoqiang
Wu, Xiangyu
Liu, Wei
Wu, Rongde
author_sort He, Yan
collection PubMed
description BACKGROUND: To observe the postoperative recovery following ureteral dilation in primary obstructive megaureter (POM) after ureteral implantation, and evaluate the risk factors affecting ureter diameter resolution. MATERIALS AND METHODS: A retrospective study was performed in patients with POM who underwent ureteral reimplantation using the Cohen procedure. Patient characteristics, perioperative parameters, and postoperative outcomes were also analysed. A widest ureteral diameter of <7 mm was defined as a normal shape and outcome. Survival time was defined as the time from surgery to ureteral dilation recovery or to the last follow-up. RESULTS: A total of 49 patients (54 ureters) were included in the analysis. The survival time ranged from 1 to 53 months. The shapes of a total of 47 (87.04%) megaureters recovered, and most (29/47) resolutions happened within 6 months after surgery. In the univariate analysis, bilateral ureterovesical reimplantation (p = 0.015), ureteral terminal tapering (p = 0.019), weight (p = 0.036), and age (p = 0.015) were associated with the recovery time of ureteral dilation. A delayed recovery of ureteral diameter was noted in bilateral reimplantation (HR = 0.336, p = 0.017) using multivariate Cox regression. CONCLUSIONS: Ureteral dilation in POM mostly returned to normal within six postoperative months. Moreover, bilateral ureterovesical reimplantation is a risk factor for delayed postoperative recovery of ureter dilation in POM.
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spelling pubmed-103265132023-07-08 Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter He, Yan Wu, Xuemin Xu, Yingrui Liu, Zhaoquan Du, Guoqiang Wu, Xiangyu Liu, Wei Wu, Rongde Front Pediatr Pediatrics BACKGROUND: To observe the postoperative recovery following ureteral dilation in primary obstructive megaureter (POM) after ureteral implantation, and evaluate the risk factors affecting ureter diameter resolution. MATERIALS AND METHODS: A retrospective study was performed in patients with POM who underwent ureteral reimplantation using the Cohen procedure. Patient characteristics, perioperative parameters, and postoperative outcomes were also analysed. A widest ureteral diameter of <7 mm was defined as a normal shape and outcome. Survival time was defined as the time from surgery to ureteral dilation recovery or to the last follow-up. RESULTS: A total of 49 patients (54 ureters) were included in the analysis. The survival time ranged from 1 to 53 months. The shapes of a total of 47 (87.04%) megaureters recovered, and most (29/47) resolutions happened within 6 months after surgery. In the univariate analysis, bilateral ureterovesical reimplantation (p = 0.015), ureteral terminal tapering (p = 0.019), weight (p = 0.036), and age (p = 0.015) were associated with the recovery time of ureteral dilation. A delayed recovery of ureteral diameter was noted in bilateral reimplantation (HR = 0.336, p = 0.017) using multivariate Cox regression. CONCLUSIONS: Ureteral dilation in POM mostly returned to normal within six postoperative months. Moreover, bilateral ureterovesical reimplantation is a risk factor for delayed postoperative recovery of ureter dilation in POM. Frontiers Media S.A. 2023-06-23 /pmc/articles/PMC10326513/ /pubmed/37425259 http://dx.doi.org/10.3389/fped.2023.1164474 Text en © 2023 He, Wu, Xu, Liu, Du, Wu, Liu and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
He, Yan
Wu, Xuemin
Xu, Yingrui
Liu, Zhaoquan
Du, Guoqiang
Wu, Xiangyu
Liu, Wei
Wu, Rongde
Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
title Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
title_full Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
title_fullStr Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
title_full_unstemmed Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
title_short Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
title_sort ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326513/
https://www.ncbi.nlm.nih.gov/pubmed/37425259
http://dx.doi.org/10.3389/fped.2023.1164474
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