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An overview of the role of telomeres and telomerase in pre‑neoplastic lesions (Review)
Telomeres are tandem repeats of DNA sequences protecting the end of linear chromosomes. Replicative senescence due to telomere attrition is considered a tumor-preventing mechanism in differentiated somatic cells. However, telomere shortening is associated with genome instability and several disease...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326563/ https://www.ncbi.nlm.nih.gov/pubmed/37424625 http://dx.doi.org/10.3892/mco.2023.2657 |