Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis

Multiple studies have identified metabolic changes within the tumor and its microenvironment during carcinogenesis. Yet, the mechanisms by which tumors affect the host metabolism are unclear. We find that systemic inflammation induced by cancer leads to liver infiltration of myeloid cells at early e...

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Detalles Bibliográficos
Autores principales: Goldman, Omer, Adler, Lital N., Hajaj, Emma, Croese, Tommaso, Darzi, Naama, Galai, Sivan, Tishler, Hila, Ariav, Yarden, Lavie, Dor, Fellus-Alyagor, Liat, Oren, Roni, Kuznetsov, Yuri, David, Eyal, Jaschek, Rami, Stossel, Chani, Singer, Oded, Malitsky, Sergey, Barak, Renana, Seger, Rony, Erez, Neta, Amit, Ido, Tanay, Amos, Saada, Ann, Golan, Talia, Rubinek, Tamar, Sang Lee, Joo, Ben-Shachar, Shay, Wolf, Ido, Erez, Ayelet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326600/
https://www.ncbi.nlm.nih.gov/pubmed/36972357
http://dx.doi.org/10.1158/2159-8290.CD-22-1062

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