Integrative Analysis of a Large Real-World Cohort of Small Cell Lung Cancer Identifies Distinct Genetic Subtypes and Insights into Histologic Transformation

Small cell lung cancer (SCLC) is a recalcitrant neuroendocrine carcinoma with dismal survival outcomes. A major barrier in the field has been the relative paucity of human tumors studied. Here we provide an integrated analysis of 3,600 “real-world” SCLC cases. This large cohort allowed us to identif...

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Detalles Bibliográficos
Autores principales: Sivakumar, Smruthy, Moore, Jay A., Montesion, Meagan, Sharaf, Radwa, Lin, Douglas I., Colón, Caterina I., Fleishmann, Zoe, Ebot, Ericka M., Newberg, Justin Y., Mills, Jennifer M., Hegde, Priti S., Pan, Quintin, Dowlati, Afshin, Frampton, Garrett M., Sage, Julien, Lovly, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326603/
https://www.ncbi.nlm.nih.gov/pubmed/37062002
http://dx.doi.org/10.1158/2159-8290.CD-22-0620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326603/
https://www.ncbi.nlm.nih.gov/pubmed/37062002
http://dx.doi.org/10.1158/2159-8290.CD-22-0620

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