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Integrative Analysis of a Large Real-World Cohort of Small Cell Lung Cancer Identifies Distinct Genetic Subtypes and Insights into Histologic Transformation
Small cell lung cancer (SCLC) is a recalcitrant neuroendocrine carcinoma with dismal survival outcomes. A major barrier in the field has been the relative paucity of human tumors studied. Here we provide an integrated analysis of 3,600 “real-world” SCLC cases. This large cohort allowed us to identif...
Autores principales: | Sivakumar, Smruthy, Moore, Jay A., Montesion, Meagan, Sharaf, Radwa, Lin, Douglas I., Colón, Caterina I., Fleishmann, Zoe, Ebot, Ericka M., Newberg, Justin Y., Mills, Jennifer M., Hegde, Priti S., Pan, Quintin, Dowlati, Afshin, Frampton, Garrett M., Sage, Julien, Lovly, Christine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326603/ https://www.ncbi.nlm.nih.gov/pubmed/37062002 http://dx.doi.org/10.1158/2159-8290.CD-22-0620 |
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