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Atrial arrhythmias following lung transplant: a single pediatric center experience

BACKGROUND: Outcomes after lung transplant (LTx) in children have slowly improved. Although atrial arrhythmia (AA) is a common and adverse complication following LTx among adults, there is limited data on pediatric recipients. We detail our pediatric single-center experience while providing further...

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Autores principales: Sill, Jordan, Baskar, Shankar, Zang, Huaiyu, Spar, David, Iliopoulos, Ilias, Morales, David L. S., Hayes, Don, Koh, Wonshill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326625/
https://www.ncbi.nlm.nih.gov/pubmed/37425256
http://dx.doi.org/10.3389/fped.2023.1161129
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author Sill, Jordan
Baskar, Shankar
Zang, Huaiyu
Spar, David
Iliopoulos, Ilias
Morales, David L. S.
Hayes, Don
Koh, Wonshill
author_facet Sill, Jordan
Baskar, Shankar
Zang, Huaiyu
Spar, David
Iliopoulos, Ilias
Morales, David L. S.
Hayes, Don
Koh, Wonshill
author_sort Sill, Jordan
collection PubMed
description BACKGROUND: Outcomes after lung transplant (LTx) in children have slowly improved. Although atrial arrhythmia (AA) is a common and adverse complication following LTx among adults, there is limited data on pediatric recipients. We detail our pediatric single-center experience while providing further insights on occurrence and management of AA following LTx. METHODS: A retrospective analysis of LTx recipients at a pediatric LTx program from 2014 to 2022 was performed. We investigated timing of occurrence and management of AA following LTx, and its effect on post-LTx outcome. RESULTS: Three out of nineteen (15%) pediatric LTx recipients developed AA. The timing of occurrence was 9–10 days following LTx. Those patients in the older age group (age >12 years old) were the only ones who developed AA. Developing AA did not have a negative effect on hospital stay duration or short-term mortality. All LTx recipients with AA were discharged home on therapy that was discontinued at 6 months for those who was on mono-therapy without recurrence of AA. CONCLUSIONS: AA is an early post-operative complication in older children and younger adults undergoing LTx at a pediatric center. Early recognition and aggressive management can mitigate any morbidity or mortality. Future investigations should explore factors that place this population at risk for AA in order to prevent this complication post-operatively.
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spelling pubmed-103266252023-07-08 Atrial arrhythmias following lung transplant: a single pediatric center experience Sill, Jordan Baskar, Shankar Zang, Huaiyu Spar, David Iliopoulos, Ilias Morales, David L. S. Hayes, Don Koh, Wonshill Front Pediatr Pediatrics BACKGROUND: Outcomes after lung transplant (LTx) in children have slowly improved. Although atrial arrhythmia (AA) is a common and adverse complication following LTx among adults, there is limited data on pediatric recipients. We detail our pediatric single-center experience while providing further insights on occurrence and management of AA following LTx. METHODS: A retrospective analysis of LTx recipients at a pediatric LTx program from 2014 to 2022 was performed. We investigated timing of occurrence and management of AA following LTx, and its effect on post-LTx outcome. RESULTS: Three out of nineteen (15%) pediatric LTx recipients developed AA. The timing of occurrence was 9–10 days following LTx. Those patients in the older age group (age >12 years old) were the only ones who developed AA. Developing AA did not have a negative effect on hospital stay duration or short-term mortality. All LTx recipients with AA were discharged home on therapy that was discontinued at 6 months for those who was on mono-therapy without recurrence of AA. CONCLUSIONS: AA is an early post-operative complication in older children and younger adults undergoing LTx at a pediatric center. Early recognition and aggressive management can mitigate any morbidity or mortality. Future investigations should explore factors that place this population at risk for AA in order to prevent this complication post-operatively. Frontiers Media S.A. 2023-06-23 /pmc/articles/PMC10326625/ /pubmed/37425256 http://dx.doi.org/10.3389/fped.2023.1161129 Text en © 2023 Sill, Baskar, Zang, Spar, Iliopoulos, Morales, Hayes Jr and Koh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Sill, Jordan
Baskar, Shankar
Zang, Huaiyu
Spar, David
Iliopoulos, Ilias
Morales, David L. S.
Hayes, Don
Koh, Wonshill
Atrial arrhythmias following lung transplant: a single pediatric center experience
title Atrial arrhythmias following lung transplant: a single pediatric center experience
title_full Atrial arrhythmias following lung transplant: a single pediatric center experience
title_fullStr Atrial arrhythmias following lung transplant: a single pediatric center experience
title_full_unstemmed Atrial arrhythmias following lung transplant: a single pediatric center experience
title_short Atrial arrhythmias following lung transplant: a single pediatric center experience
title_sort atrial arrhythmias following lung transplant: a single pediatric center experience
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326625/
https://www.ncbi.nlm.nih.gov/pubmed/37425256
http://dx.doi.org/10.3389/fped.2023.1161129
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