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Long noncoding RNAs, glucose metabolism and cancer (Review)
Cancer is a serious and potentially life-threatening disease, which, despite numerous advances over several decades, remains a challenge to treat that challenging to detect at an early stage or treat during the later stages. Long noncoding RNAs are >200 nucleotides long and do not possess protein...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326653/ https://www.ncbi.nlm.nih.gov/pubmed/37427347 http://dx.doi.org/10.3892/ol.2023.13925 |
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author | Hou, Xin-Rui Zhang, Zhen-Dong Cao, Xiao-Lan Wang, Xiao-Ping |
author_facet | Hou, Xin-Rui Zhang, Zhen-Dong Cao, Xiao-Lan Wang, Xiao-Ping |
author_sort | Hou, Xin-Rui |
collection | PubMed |
description | Cancer is a serious and potentially life-threatening disease, which, despite numerous advances over several decades, remains a challenge to treat that challenging to detect at an early stage or treat during the later stages. Long noncoding RNAs are >200 nucleotides long and do not possess protein-coding capacity, instead regulating cellular processes, such as proliferation, differentiation, maturation, apoptosis, metastasis, and sugar metabolism. Several studies have shown the role of lncRNAs and glucose metabolism in regulating several key glycolytic enzymes and the activity of multiple functional signaling pathways during tumor progression. Thus, it is possible to further learn about the effects of lncRNA and glycolytic metabolism on tumor diagnosis, treatment, and prognosis through a thorough investigation of the lncRNA expression profiles and glycolytic metabolism in tumors. This may provide a novel strategy for improving the management of several types of cancer. |
format | Online Article Text |
id | pubmed-10326653 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-103266532023-07-08 Long noncoding RNAs, glucose metabolism and cancer (Review) Hou, Xin-Rui Zhang, Zhen-Dong Cao, Xiao-Lan Wang, Xiao-Ping Oncol Lett Review Cancer is a serious and potentially life-threatening disease, which, despite numerous advances over several decades, remains a challenge to treat that challenging to detect at an early stage or treat during the later stages. Long noncoding RNAs are >200 nucleotides long and do not possess protein-coding capacity, instead regulating cellular processes, such as proliferation, differentiation, maturation, apoptosis, metastasis, and sugar metabolism. Several studies have shown the role of lncRNAs and glucose metabolism in regulating several key glycolytic enzymes and the activity of multiple functional signaling pathways during tumor progression. Thus, it is possible to further learn about the effects of lncRNA and glycolytic metabolism on tumor diagnosis, treatment, and prognosis through a thorough investigation of the lncRNA expression profiles and glycolytic metabolism in tumors. This may provide a novel strategy for improving the management of several types of cancer. D.A. Spandidos 2023-06-22 /pmc/articles/PMC10326653/ /pubmed/37427347 http://dx.doi.org/10.3892/ol.2023.13925 Text en Copyright: © Hou et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Review Hou, Xin-Rui Zhang, Zhen-Dong Cao, Xiao-Lan Wang, Xiao-Ping Long noncoding RNAs, glucose metabolism and cancer (Review) |
title | Long noncoding RNAs, glucose metabolism and cancer (Review) |
title_full | Long noncoding RNAs, glucose metabolism and cancer (Review) |
title_fullStr | Long noncoding RNAs, glucose metabolism and cancer (Review) |
title_full_unstemmed | Long noncoding RNAs, glucose metabolism and cancer (Review) |
title_short | Long noncoding RNAs, glucose metabolism and cancer (Review) |
title_sort | long noncoding rnas, glucose metabolism and cancer (review) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326653/ https://www.ncbi.nlm.nih.gov/pubmed/37427347 http://dx.doi.org/10.3892/ol.2023.13925 |
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