Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies

Over the past decade there has been an interest in understanding the role of gut microbiota in the pathogenesis of AF. A number of studies have linked the gut microbiota to the occurrence of traditional AF risk factors such as hypertension and obesity. However, it remains unclear whether gut dysbios...

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Autores principales: Al-Kaisey, Ahmed M, Figgett, William, Hawson, Joshua, Mackay, Fabienne, Joseph, Stephen A, Kalman, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2023
Materias:
Atrial Fibrillation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326663/
https://www.ncbi.nlm.nih.gov/pubmed/37427301
http://dx.doi.org/10.15420/aer.2022.33
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author Al-Kaisey, Ahmed M
Figgett, William
Hawson, Joshua
Mackay, Fabienne
Joseph, Stephen A
Kalman, Jonathan M
author_facet Al-Kaisey, Ahmed M
Figgett, William
Hawson, Joshua
Mackay, Fabienne
Joseph, Stephen A
Kalman, Jonathan M
author_sort Al-Kaisey, Ahmed M
collection PubMed
description Over the past decade there has been an interest in understanding the role of gut microbiota in the pathogenesis of AF. A number of studies have linked the gut microbiota to the occurrence of traditional AF risk factors such as hypertension and obesity. However, it remains unclear whether gut dysbiosis has a direct effect on arrhythmogenesis in AF. This article describes the current understanding of the effect of gut dysbiosis and associated metabolites on AF. In addition, current therapeutic strategies and future directions are discussed.
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spelling pubmed-103266632023-07-08 Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies Al-Kaisey, Ahmed M Figgett, William Hawson, Joshua Mackay, Fabienne Joseph, Stephen A Kalman, Jonathan M Arrhythm Electrophysiol Rev Atrial Fibrillation Over the past decade there has been an interest in understanding the role of gut microbiota in the pathogenesis of AF. A number of studies have linked the gut microbiota to the occurrence of traditional AF risk factors such as hypertension and obesity. However, it remains unclear whether gut dysbiosis has a direct effect on arrhythmogenesis in AF. This article describes the current understanding of the effect of gut dysbiosis and associated metabolites on AF. In addition, current therapeutic strategies and future directions are discussed. Radcliffe Cardiology 2023-04-19 /pmc/articles/PMC10326663/ /pubmed/37427301 http://dx.doi.org/10.15420/aer.2022.33 Text en Copyright © 2023, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Atrial Fibrillation
Al-Kaisey, Ahmed M
Figgett, William
Hawson, Joshua
Mackay, Fabienne
Joseph, Stephen A
Kalman, Jonathan M
Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
title Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
title_full Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
title_fullStr Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
title_full_unstemmed Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
title_short Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
title_sort gut microbiota and atrial fibrillation: pathogenesis, mechanisms and therapies
topic Atrial Fibrillation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326663/
https://www.ncbi.nlm.nih.gov/pubmed/37427301
http://dx.doi.org/10.15420/aer.2022.33
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