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Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers
Allogeneic human pluripotent stem cell (hPSC)-derived cells and tissues for therapeutic transplantation must necessarily overcome immunological rejection by the recipient. To define these barriers and to create cells capable of evading rejection for preclinical testing in immunocompetent mouse model...
Autores principales: | Pizzato, Hannah A., Alonso-Guallart, Paula, Woods, James, Johannesson, Bjarki, Connelly, Jon P., Fehniger, Todd A., Atkinson, John P., Pruett-Miller, Shondra M., Monsma, Frederick J., Bhattacharya, Deepta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326974/ https://www.ncbi.nlm.nih.gov/pubmed/37425790 http://dx.doi.org/10.1101/2023.06.27.546594 |
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