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Distinct Conformations of Mirabegron Determined by MicroED

Mirabegron, commonly known as "Myrbetriq", has been widely prescribed as a medicine for overactive bladder syndrome for over a decade. However, the structure of the drug and what conformational changes it may undergo upon binding its receptor remain unknown. In this study, we employed micr...

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Detalles Bibliográficos
Autores principales: Lin, Jieye, Unge, Johan, Gonen, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326998/
https://www.ncbi.nlm.nih.gov/pubmed/37425799
http://dx.doi.org/10.1101/2023.06.28.546957

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