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Distinct Conformations of Mirabegron Determined by MicroED
Mirabegron, commonly known as "Myrbetriq", has been widely prescribed as a medicine for overactive bladder syndrome for over a decade. However, the structure of the drug and what conformational changes it may undergo upon binding its receptor remain unknown. In this study, we employed micr...
Autores principales: | Lin, Jieye, Unge, Johan, Gonen, Tamir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326998/ https://www.ncbi.nlm.nih.gov/pubmed/37425799 http://dx.doi.org/10.1101/2023.06.28.546957 |
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