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Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension

Glaucoma leads to vision loss due to retinal ganglion cell death. Astrocyte reactivity contributes to neurodegeneration. Our recent study found that lipoxin B(4) (LXB(4)), produced by retinal astrocytes, has direct neuroprotective actions on retinal ganglion cells. In this study, we aimed to investi...

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Detalles Bibliográficos
Autores principales: Karnam, Shruthi, Maurya, Shubham, Ng, Elainna, Choudhary, Amodini, Thobani, Arzin, Flanagan, John G, Gronert, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327029/
https://www.ncbi.nlm.nih.gov/pubmed/37425861
http://dx.doi.org/10.1101/2023.06.22.546157