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Focusing antibody responses to the fusion peptide in rhesus macaques
Immunodominance of antibodies targeting non-neutralizing epitopes and the high level of somatic hypermutation within germinal centers (GCs) required for most HIV broadly neutralizing antibodies (bnAbs) are major impediments to the development of an effective HIV vaccine. Rational protein vaccine des...
Autores principales: | Cottrell, Christopher A., Pratap, Payal P., Cirelli, Kimberly M., Carnathan, Diane G., Enemuo, Chiamaka A, Antanasijevic, Aleksandar, Ozorowski, Gabriel, Sewall, Leigh M., Gao, Hongmei, Greene, Kelli M., Allen, Joel D., Ngo, Julia T., Choe, Yury, Nogal, Bartek, Silva, Murillo, Bhiman, Jinal, Pauthner, Matthias, Irvine, Darrell J., Montefiori, David, Crispin, Max, Burton, Dennis R., Silvestri, Guido, Crotty, Shane, Ward, Andrew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327030/ https://www.ncbi.nlm.nih.gov/pubmed/37425865 http://dx.doi.org/10.1101/2023.06.26.545779 |
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