Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential

Despite the wide availability of several safe and effective vaccines that can prevent severe COVID-19 disease, the emergence of SARS-CoV-2 variants of concern (VOC) that can partially evade vaccine immunity remains a global health concern. In addition, the emergence of highly mutated and neutralizat...

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Detalles Bibliográficos
Autores principales: Martinez, David R., Moreira, Fernando R., Zweigart, Mark R., Gully, Kendra L., De la Cruz, Gabriela, Brown, Ariane J., Adams, Lily E., Catanzaro, Nicholas, Yount, Boyd, Baric, Thomas J., Mallory, Michael L., Conrad, Helen, May, Samantha R., Dong, Stephanie, Scobey, D. Trevor, Montgomery, Stephanie A., Perry, Jason, Babusis, Darius, Barrett, Kimberly T., Nguyen, Anh-Hoa, Nguyen, Anh-Quan, Kalla, Rao, Bannister, Roy, Bilello, John P., Feng, Joy Y., Cihlar, Tomas, Baric, Ralph S., Mackman, Richard L., Schäfer, Alexandra, Sheahan, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327034/
https://www.ncbi.nlm.nih.gov/pubmed/37425890
http://dx.doi.org/10.1101/2023.06.27.546784

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