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Synapsin E-domain is essential for α-synuclein function

The cytosolic proteins synucleins and synapsins are thought to play cooperative roles in regulating synaptic vesicle (SV) recycling, but mechanistic insight is lacking. Here we identify the synapsin E-domain as an essential functional binding-partner of α-synuclein (α-syn). Synapsin E-domain allows...

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Detalles Bibliográficos
Autores principales: Stavsky, Alexandra, Parra-Rivas, Leonardo A., Tal, Shani, Madhivanan, Kayalvizhi, Roy, Subhojit, Gitler, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327093/
https://www.ncbi.nlm.nih.gov/pubmed/37425805
http://dx.doi.org/10.1101/2023.06.24.546170

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