Post-exposure intranasal IFNα suppresses replication and neuroinvasion of Venezuelan Equine Encephalitis virus within olfactory sensory neurons

Venezuelan Equine Encephalitis virus (VEEV) may enter the central nervous system (CNS) within olfactory sensory neurons (OSN) that originate in the nasal cavity after intranasal exposure. While it is known that VEEV has evolved several mechanisms to inhibit type I interferon (IFN) signaling within i...

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Detalles Bibliográficos
Autores principales: Cain, Matthew D., Klein, N. Rubin, Jiang, Xiaoping, Klein, Robyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327097/
https://www.ncbi.nlm.nih.gov/pubmed/37425867
http://dx.doi.org/10.1101/2023.06.30.547169

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