Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. However, the delivery of transgenes and potential risk of teratoma formation present challenges for in vivo appl...

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Detalles Bibliográficos
Autores principales: Mitchell, Wayne, Goeminne, Ludger J.E., Tyshkovskiy, Alexander, Zhang, Sirui, Paulo, Joao A., Pierce, Kerry A., Choy, Angelina H., Clish, Clary B., Gygi, Steven P., Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327104/
https://www.ncbi.nlm.nih.gov/pubmed/37425825
http://dx.doi.org/10.1101/2023.06.30.546730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327104/
https://www.ncbi.nlm.nih.gov/pubmed/37425825
http://dx.doi.org/10.1101/2023.06.30.546730

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