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Genetic risk assessment of lethal prostate cancer using polygenic risk score and hereditary cancer susceptibility genes

BACKGROUND: The genetic risk of aggressive prostate cancer (PCa) is hard to be assessed due to the lack of aggressiveness-related single-nucleotide polymorphisms (SNPs). Prostate volume (PV) is a potential well-established risk factor for aggressive PCa, we hypothesize that polygenic risk score (PRS...

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Detalles Bibliográficos
Autores principales:	Ruan, Xiaohao, Huang, Da, Huang, Jingyi, Tsu, James Hok-Leung, Na, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327136/ https://www.ncbi.nlm.nih.gov/pubmed/37415201 http://dx.doi.org/10.1186/s12967-023-04316-y

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