Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals

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MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression that play critical roles in development and disease. Target-directed miRNA degradation (TDMD), a pathway in which miRNAs that bind to specialized targets with extensive complementarity are rapidly decayed, has emerged as a pot...

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Detalles Bibliográficos
Autores principales: Jones, Benjamin T, Han, Jaeil, Zhang, He, Hammer, Robert E., Evers, Bret M., Rakheja, Dinesh, Acharya, Asha, Mendell, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327180/
https://www.ncbi.nlm.nih.gov/pubmed/37425885
http://dx.doi.org/10.1101/2023.06.26.546601
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