Visualizing alpha-synuclein and iron deposition in M83 mouse model of Parkinson’s disease in vivo

BACKGROUND: Abnormal alpha-synuclein and iron accumulation in the brain play an important role in Parkinson’s disease (PD). Herein, we aim at visualizing alpha-synuclein inclusions and iron deposition in the brains of M83 (A53T) mouse models of PD in vivo. METHODS: Fluorescently labelled pyrimidoind...

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Detalles Bibliográficos
Autores principales: Straumann, Nadja, Combes, Benjamin F., Dean Ben, Xose Luis, Sternke-Hoffmann, Rebecca, Gerez, Juan A., Dias, Ines, Chen, Zhenyue, Watts, Benjamin, Rostami, Iman, Shi, Kuangyu, Rominger, Axel, Baumann, Christian R, Luo, Jinghui, Noain, Daniela, Nitsch, Roger M., Okamura, Nobuyuki, Razansky, Daniel, Ni, Ruiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327184/
https://www.ncbi.nlm.nih.gov/pubmed/37425954
http://dx.doi.org/10.1101/2023.06.28.546962

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