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SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity

The glycosylation of viral envelope proteins can play important roles in virus biology and immune evasion. The spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) includes 22 N-linked glycosylation sequons and 17 O-linked glycosites. Here, we investigated the effec...

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Detalles Bibliográficos
Autores principales: Zhang, Fengwen, Schmidt, Fabian, Muecksch, Frauke, Wang, Zijun, Gazumyan, Anna, Nussenzweig, Michel C., Gaebler, Christian, Caskey, Marina, Hatziioannou, Theodora, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327196/
https://www.ncbi.nlm.nih.gov/pubmed/37425700
http://dx.doi.org/10.1101/2023.06.30.547241