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Inflammatory macrophages prevent colonic goblet and enteroendocrine cell differentiation through Notch signaling
Inflammatory macrophages in the intestine are a key pathogenic factor driving inflammatory bowel disease (IBD). Here, we report the role of inflammatory macrophage-mediated notch signaling on secretory lineage differentiation in the intestinal epithelium. Utilizing IL-10-deficient (Il10(−/−)) mice,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327198/ https://www.ncbi.nlm.nih.gov/pubmed/37425818 http://dx.doi.org/10.1101/2023.06.29.547119 |