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Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread. Here, we show that Omicron exhibits increased infectivity in primary adult upper airway tissue relative to Delta. Using recombinan...

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Detalles Bibliográficos
Autores principales: Shi, Guoli, Li, Tiansheng, Lai, Kin Kui, Johnson, Reed F., Yewdell, Jonathan W, Compton, Alex A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327209/
https://www.ncbi.nlm.nih.gov/pubmed/37425811
http://dx.doi.org/10.1101/2023.05.06.539698