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Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue
Omicron emerged following COVID-19 vaccination campaigns, displaced previous SARS-CoV-2 variants of concern worldwide, and gave rise to lineages that continue to spread. Here, we show that Omicron exhibits increased infectivity in primary adult upper airway tissue relative to Delta. Using recombinan...
Autores principales: | Shi, Guoli, Li, Tiansheng, Lai, Kin Kui, Johnson, Reed F., Yewdell, Jonathan W, Compton, Alex A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327209/ https://www.ncbi.nlm.nih.gov/pubmed/37425811 http://dx.doi.org/10.1101/2023.05.06.539698 |
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