Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

A principal protective component of the mammalian blood-brain barrier (BBB) is the high expression of the multidrug efflux transporters P-glycoprotein (P-gp, encoded by ABCB1) and ABCG2 (encoded by ABCG2) on the luminal surface of endothelial cells. The zebrafish P-gp homolog Abcb4 is expressed at t...

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Detalles Bibliográficos
Autores principales: Thomas, Joanna R., Frye, William J. E., Robey, Robert W., Warner, Andrew C., Butcher, Donna, Matta, Jennifer L., Morgan, Tamara C., Edmondson, Elijah F., Gottesman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327217/
https://www.ncbi.nlm.nih.gov/pubmed/37425689
http://dx.doi.org/10.1101/2023.05.18.539313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327217/
https://www.ncbi.nlm.nih.gov/pubmed/37425689
http://dx.doi.org/10.1101/2023.05.18.539313

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