Meta-analysis of CYP2C19 and CYP2D6 metabolic activity on antidepressant response from 13 clinical studies

Cytochrome P450 enzymes including CYP2C19 and CYP2D6 are important for antidepressant metabolism and polymorphisms of these genes have been determined to predict metabolite levels. Nonetheless, more evidence is needed to understand the impact of genetic variations on antidepressant response. In this...

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Detalles Bibliográficos
Autores principales: Li, Danyang, Pain, Oliver, Fabbri, Chiara, Wong, Win Lee Edwin, Lo, Chris Wai Hang, Ripke, Stephan, Cattaneo, Annamaria, Souery, Daniel, Dernovsek, Mojca Z., Henigsberg, Neven, Hauser, Joanna, Lewis, Glyn, Mors, Ole, Perroud, Nader, Rietschel, Marcella, Uher, Rudolf, Maier, Wolfgang, Aitchison, Katherine J., Baune, Bernhard T., Biernacka, Joanna M., Bondolfi, Guido, Domschke, Katharina, Kato, Masaki, Liu, Yu-Li, Serretti, Alessandro, Tsai, Shih-Jen, Weinshilboum, Richard, McIntosh, Andrew M., Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327261/
https://www.ncbi.nlm.nih.gov/pubmed/37425775
http://dx.doi.org/10.1101/2023.06.26.23291890

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